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News
Carbon Dots Emerge as a Powerful Weapon Against Superbugs and Biofilms
1+ day, 11+ hour ago (75+ words) A new comprehensive review published in the Journal of Nanoparticle Research surveys one of the most quietly promising corners of nanomedicine: carbon dots, nanoscale specks of carbon that are showing remarkable ability to kill bacteria and dismantle the sticky biofilms…...
Your Zip Code May Shape Your Breast Cancer Tumor’s Genetics and Your
1+ day, 11+ hour ago (617+ words) A landmark multi-institution study has revealed that the neighborhood a patient with metastatic breast cancer lives in may be written into the biology of the tumor itself....
Leadership, Not Resilience Training, May Be the Key to Curing Physician
1+ day, 11+ hour ago (671+ words) Pediatric radiology is, by almost any measure, deeply meaningful work. Radiologists, technologists, nurses, and child life specialists spend their careers peering inside the bodies of sick children, catching diseases early, guiding treatment decisions, and supporting families through some of the…...
Light-Activated Cancer Therapy Shows Power to Trigger Body-Wide Immune
1+ day, 11+ hour ago (431+ words) Photodynamic therapy, or PDT, has long been regarded as a precisely local cancer treatment: a photosensitizing drug is delivered to a tumor, light of a specific wavelength activates it, and the resulting reactive oxygen species destroy the illuminated cells....
Copper and Iron Cell Death Pathways Offer a New Two-Front Attack on Liver
1+ day, 13+ hour ago (55+ words) Hepatocellular carcinoma, the most common form of primary liver cancer, remains one of the world’s most lethal malignancies, and its treatment options have changed surprisingly little over the past two decades. Now, a review published in Medical Oncology argues that…...
Chemists Craft a One-Handed Molecule That Disarms a Cell-Death Protein
1+ day, 13+ hour ago (661+ words) A single protein called BAX sits at the gateway between life and death for human cells. When tissues are injured, stressed, or deprived of oxygen, BAX springs into action, punching holes in the outer membrane of mitochondria and triggering the…...
Shifting Identities: How Lung Cancer Cells Change Face to Outsmart
1+ day, 13+ hour ago (69+ words) Small-cell lung cancer has long been one of oncology’s most punishing adversaries. It grows with astonishing speed, spreads early, and presents a treatment paradox that has frustrated clinicians for decades: at diagnosis, tumors melt away under platinum-based chemotherapy, yet relapse…...
Children’s Aerobic Fitness Declines in Final Primary School Years,
1+ day, 13+ hour ago (611+ words) One of the most detailed long-term portraits of children’s aerobic fitness ever assembled suggests a troubling pattern in the final years of primary school. Researchers tracking hundreds of Norwegian children from first through sixth grade found that peak oxygen uptake,…...
Receptor Occupancy Fails to Predict Immune Activation in Pembrolizumab
1+ day, 13+ hour ago (55+ words) Pembrolizumab, one of the most widely prescribed cancer immunotherapies in the world, has long been dosed on the assumption that saturating the PD-1 receptor on T cells is the key to unlocking the immune system against tumours. A new translational…...
Engineered T Cell Receptors With Built-In ICOS Deliver Long-Lasting
1+ day, 13+ hour ago (120+ words) Adoptive T cell therapy has delivered striking remissions in some blood cancers, but its promise in solid tumors has been repeatedly undermined by a stubborn problem: the therapeutic cells do not last. Engineered T cells that flood a tumor and…...